Adaptation and Pathogenesis of Microorganisms
The CNRS UMR5163 laboratory is dedicated to research in the field of microbiology, using an integrative approach aimed at understanding adaptive processes and pathogenesis of microorganisms (bacteria, parasites, prion, new and reemerging infectious agents). Our investigation is based on comparative genomics, studies of evolution, analysis of virulence factors and phenomena leading to susceptibility to pathogens (species barrier, innate and adaptive immunity). Our approach, using biochemical, cellular, and transgenic animal models, goes from studies of specific processes towards global analysis and modelling. This knowledge should be beneficial for development of preventive measures, understanding risks and anticipating treatments.
ORGANISATION
Parasitology
Intracellular parasitism
Epigenetic and parasites
Differentiation
Bacteriology
Control of gene expression
Dynamics and evolution of the bacterial genome
Prion
Transmission and pathogenesis of transmissible spongiform encephalopathies diseases
The research groups share multidisciplinary technological facilities such as
- Cell culture (L2 laboratories)
- Protein expression and purification
- Cell sorting and fluorescence analysis
- Animal housing and transgenesis platform (A2 & A3 security )
The unit has privilege collaborations with a network of major regional facilities platform such as :
The laboratory has obtained funding from the National Research Agency, the European Commission, Innovations in Infectiology RTRA (FINOVI), the Rhône-Alpes Region, Grenoble Alpes Metropole, the research cluster in infectiology, and Lyon Biopole center of excellence.
The Jean Roget Institute is developing to R&D programs in the fields of infectious diseases and microbiology. We are able to offer attractive and competitive environment in this scientific area. Please contact the board for collaboration or to join us.
Updated the
18/12/07
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